Cutaneous Albinism

《英文msh詞典》Cutaneous Albinism
[入口詞] Cutaneous Albinism
[主題詞] Piebaldism
[中文釋義] 皮膚白化病
[英文釋義] Autosomal dominant,congenital disorder characterized by localized hypomelanosis of the skin and hair. The most familiar feature is a white forelock presenting in 80 to 90 percent of the patients. The underlying defect is possibly related to the differentiation and migration of melanoblasts,as well as to defective development of the neural crest (neurocristopathy). Piebaldism may be closely related to Waardenburg's syndrome.